CBD stops brain mechanisms that contribute to seizures by increasing the release of the inhibitory neurotransmitter GABA. CBD increases anandamide in the brain. Increased levels of anandamide in the brain have been associated with decreased psychotic symptoms. Now that you know some basic differences between CBD and THC, let’s find out more about CBD and the brain.
While most of the research available today has focused on understanding the relationship between humans and THC, CBD in the brain has recently been shown to have great potential with regards to its medical versatility. Neurodegenerative disorders can be curbed through the use of CBD as a complementary treatment option; it is important to understand that CBD possesses anti-inflammatory properties, meaning that inflammation-related brain health problems can be significantly reduced. Researchers believe that CBD’s ability to act on the endocannabinoid system and other signaling systems in the brain may provide benefits to those suffering from neurological disorders. CBD helps relieve stress by triggering the brain’s serotonin receptors to produce more cortisol.
Included were studies examining the effects of CBD on brain function in healthy volunteers and individuals diagnosed with a psychiatric disorder, including both the effects of CBD alone and in direct comparison to those induced by ∆9-tetrahydrocannabinol (THC), the main psychoactive component of Cannabis. In individuals at high clinical risk for psychosis and in patients with established psychosis, acute CBD showed intermediate brain activity compared to placebo and healthy controls during cognitive task performance. Consumers are turning to CBD to manage conditions such as migraines, brain fog, anxiety, depression and chronic pain. These qualities are related to CBD’s ability to act on brain receptors for serotonin, a neurotransmitter that regulates mood and social behavior.
A surprising effect of CBD on the brain is its ability to reduce cognitive decline and improve memory and cognitive functioning. Brain receptors are not only sensitive to neurotransmitters produced naturally in the brain, such as dopamine or serotonin, but also to chemical messengers produced outside the body, such as plant cannabinoids like THC or CBD. Research on CBD has shown that it acts as an antioxidant and that its antioxidant properties seem to provide protection to the brain. In other words, CBD protects neurons from degeneration, which helps a person’s brain stay younger.
The team concluded that CBD could “change” the level of Glx and GABA metabolites; they are known to contribute to the regulation of inhibitory and excitatory neurotransmission in autistic and typical brains.